It is on the World Health Organization's List of Essential Medicines. Spironolactone was discovered in 1957, and was introduced in 1959. Spironolactone belongs to a class of medications known as potassium-sparing diuretics. It is a steroid that blocks the effects of the hormones aldosterone and testosterone and has some estrogen-like effects.
Spironolactone has not been well studied in pregnancy and should not be used to treat high blood pressure of pregnancy. In those with liver or kidney problems, extra care should be taken. Ĭommon side effects include electrolyte abnormalities, particularly high blood potassium, nausea, vomiting, headache, rashes, and a decreased desire for sex. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of feminizing hormone therapy in trans women.
Store at room temperature away from moisture and heat.Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Hyperkalemia often has no symptoms that you will notice until your potassium levels are very low. Keep using this medicine even if you feel fine. You will need frequent medical tests to help your doctor determine how long to treat you with sodium polystyrene sulfonate. The sodium polystyrene sulfonate enema is usually followed with a second cleansing enema. You may need to hold in the enema for up to several hours. The enema will be inserted slowly while you are lying down. The rectal enema form of this medicine is usually given by a healthcare professional. Avoid inhaling the oral powder while you are preparing a dose.ĭo not mix the powder with any juice or other liquid that contains potassium, such as orange juice. To give this medicine orally: Mix the sodium polystyrene sulfonate powder with water, or with honey or jam to make it taste better.
Do not use the medicine orally or rectally in a baby who has slow digestion caused by surgery or by using other medicines. Sodium polystyrene sulfonate can be given as a liquid by mouth, through a stomach feeding tube, or as a rectal enema.ĭo not give sodium polystyrene sulfonate orally (by mouth) to a newborn baby. How is sodium polystyrene sulfonate given?įollow all directions on your prescription label and read all medication guides or instruction sheets. You may report side effects to FDA at 1-80. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Signs of stomach bleeding-bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.Ĭommon side effects of sodium polystyrene sulfonate may include: Low calcium levels-muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes) or Low potassium-leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling Severe constipation, severe stomach pain, bloating Ĭonfusion, thinking problems, feeling irritable Stop using sodium polystyrene sulfonate and call your doctor at once if you have: Sodium polystyrene sulfonate may cause serious side effects. Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat. Sodium polystyrene sulfonate side effects
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